diff --git a/yt_dlp/extractor/instagram.py b/yt_dlp/extractor/instagram.py
index 2ec24f3e7..84c1daca6 100644
--- a/yt_dlp/extractor/instagram.py
+++ b/yt_dlp/extractor/instagram.py
@@ -170,7 +170,7 @@ class InstagramIOSIE(InfoExtractor):
 
 
 class InstagramIE(InstagramBaseIE):
-    _VALID_URL = r'(?P<url>https?://(?:www\.)?instagram\.com/(?:p|tv|reel)/(?P<id>[^/?#&]+))'
+    _VALID_URL = r'(?P<url>https?://(?:www\.)?instagram\.com(?:/[^/]+)?/(?:p|tv|reel)/(?P<id>[^/?#&]+))'
     _TESTS = [{
         'url': 'https://instagram.com/p/aye83DjauH/?foo=bar#abc',
         'md5': '0d2da106a9d2631273e192b372806516',
@@ -266,6 +266,9 @@ class InstagramIE(InstagramBaseIE):
     }, {
         'url': 'https://www.instagram.com/reel/CDUMkliABpa/',
         'only_matching': True,
+    }, {
+        'url': 'https://www.instagram.com/marvelskies.fc/reel/CWqAgUZgCku/',
+        'only_matching': True,
     }]
 
     @staticmethod